BCHE hydrolyzes ASA-

Stable Identifier
R-HSA-9749609
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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BCHE hydrolyzes ASA-
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Acetylsalicylate (ASA-) is hydrolyzed by two plasma esterases. About 80% of aspirin esterase activity in the blood is due to the erythrocyte enzyme butyrylcholine esterase (pseudocholinesterase, BCHE). BCHE hydrolyzes acetylsalicylate (ASA-), producing acetate and salicylate (Rainsford et al, 1980; Costello & Green, 1983).
Literature References
Participants
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Output
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as an event of
Catalyst Activity

hydrolase activity, acting on ester bonds of BCHE [extracellular region]

Physical Entity
BCHE [extracellular region] (Homo sapiens)
Activity
hydrolase activity, acting on ester bonds (GO:0016788)
Orthologous Events
BCHE hydrolyzes ASA- (Bos taurus)
BCHE hydrolyzes ASA- (Caenorhabditis elegans)
BCHE hydrolyzes ASA- (Canis familiaris)
BCHE hydrolyzes ASA- (Drosophila melanogaster)
BCHE hydrolyzes ASA- (Gallus gallus)
BCHE hydrolyzes ASA- (Mus musculus)
BCHE hydrolyzes ASA- (Rattus norvegicus)
BCHE hydrolyzes ASA- (Xenopus tropicalis)
Cross References
Rhea
Authored
Stephan, R  (2021-08-03)
Reviewed
Huddart, R  (2021-10-13)
Created
Stephan, R  (2021-08-04)
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