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ASA- [extracellular region]
Stable Identifier
R-ALL-9749598
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
acetylsalicylate(1-)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Drug ADME (Bos taurus)
Aspirin ADME (Bos taurus)
ASA- acetylates ALB (Bos taurus)
ASA- [extracellular region]
BCHE hydrolyzes ASA- (Bos taurus)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Bos taurus)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Bos taurus)
ASA-, ST [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Bos taurus)
ASA- [extracellular region]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Proton-coupled monocarboxylate transport (Bos taurus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Bos taurus)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Bos taurus)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Caenorhabditis elegans)
Aspirin ADME (Caenorhabditis elegans)
BCHE hydrolyzes ASA- (Caenorhabditis elegans)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Caenorhabditis elegans)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Caenorhabditis elegans)
ASA-, ST [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Caenorhabditis elegans)
ASA- [extracellular region]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Proton-coupled monocarboxylate transport (Caenorhabditis elegans)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Caenorhabditis elegans)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Caenorhabditis elegans)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Canis familiaris)
Aspirin ADME (Canis familiaris)
ASA- acetylates ALB (Canis familiaris)
ASA- [extracellular region]
BCHE hydrolyzes ASA- (Canis familiaris)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Canis familiaris)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Canis familiaris)
ASA- [extracellular region]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Proton-coupled monocarboxylate transport (Canis familiaris)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Canis familiaris)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Canis familiaris)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Danio rerio)
Aspirin ADME (Danio rerio)
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Danio rerio)
ASA-, ST [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Danio rerio)
ASA- [extracellular region]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Proton-coupled monocarboxylate transport (Danio rerio)
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Danio rerio)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Drosophila melanogaster)
Aspirin ADME (Drosophila melanogaster)
BCHE hydrolyzes ASA- (Drosophila melanogaster)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Drosophila melanogaster)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Drosophila melanogaster)
ASA-, ST [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Drosophila melanogaster)
ASA- [extracellular region]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Proton-coupled monocarboxylate transport (Drosophila melanogaster)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Drosophila melanogaster)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Drosophila melanogaster)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Gallus gallus)
Aspirin ADME (Gallus gallus)
ASA- acetylates ALB (Gallus gallus)
ASA- [extracellular region]
BCHE hydrolyzes ASA- (Gallus gallus)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Gallus gallus)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Gallus gallus)
ASA-, ST [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Gallus gallus)
ASA- [extracellular region]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Proton-coupled monocarboxylate transport (Gallus gallus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Gallus gallus)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Gallus gallus)
MCT substrates [extracellular region]
ASA- [extracellular region]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) (Homo sapiens)
Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol (Homo sapiens)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Homo sapiens)
Aspirin ADME (Homo sapiens)
ASA- (GI) translocates from cytosol to extracellular region (Homo sapiens)
ASA- [extracellular region]
ASA- acetylates ALB (Homo sapiens)
ASA- [extracellular region]
Acetylsalicylic acid dissolves (Homo sapiens)
ASA- [extracellular region]
BCHE hydrolyzes ASA- (Homo sapiens)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Homo sapiens)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Homo sapiens)
ASA-, ST [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Homo sapiens)
ASA- [extracellular region]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Proton-coupled monocarboxylate transport (Homo sapiens)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Homo sapiens)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Homo sapiens)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Mus musculus)
Aspirin ADME (Mus musculus)
ASA- acetylates ALB (Mus musculus)
ASA- [extracellular region]
BCHE hydrolyzes ASA- (Mus musculus)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Mus musculus)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Mus musculus)
ASA-, ST [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Mus musculus)
ASA- [extracellular region]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Proton-coupled monocarboxylate transport (Mus musculus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Mus musculus)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Mus musculus)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Rattus norvegicus)
Aspirin ADME (Rattus norvegicus)
ASA- acetylates ALB (Rattus norvegicus)
ASA- [extracellular region]
BCHE hydrolyzes ASA- (Rattus norvegicus)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Rattus norvegicus)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Rattus norvegicus)
ASA-, ST [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Rattus norvegicus)
ASA- [extracellular region]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Proton-coupled monocarboxylate transport (Rattus norvegicus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Rattus norvegicus)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Rattus norvegicus)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Sus scrofa)
Aspirin ADME (Sus scrofa)
ASA- acetylates ALB (Sus scrofa)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Sus scrofa)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Sus scrofa)
ASA-, ST [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Sus scrofa)
ASA- [extracellular region]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Proton-coupled monocarboxylate transport (Sus scrofa)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Sus scrofa)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Sus scrofa)
MCT substrates [extracellular region]
ASA- [extracellular region]
Drug ADME (Xenopus tropicalis)
Aspirin ADME (Xenopus tropicalis)
ASA- acetylates ALB (Xenopus tropicalis)
ASA- [extracellular region]
BCHE hydrolyzes ASA- (Xenopus tropicalis)
ASA- [extracellular region]
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Xenopus tropicalis)
MCT substrates [extracellular region]
ASA- [extracellular region]
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Xenopus tropicalis)
ASA- [extracellular region]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Proton-coupled monocarboxylate transport (Xenopus tropicalis)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Xenopus tropicalis)
MCT substrates [extracellular region]
ASA- [extracellular region]
External Reference Information
External Reference
acetylsalicylate [ChEBI:13719]
Participates
as an input of
ASA- acetylates ALB (Gallus gallus)
ASA- acetylates ALB (Xenopus tropicalis)
ASA- acetylates ALB (Sus scrofa)
ASA- acetylates ALB (Bos taurus)
ASA- acetylates ALB (Canis familiaris)
ASA- acetylates ALB (Rattus norvegicus)
ASA- acetylates ALB (Mus musculus)
ASA- acetylates ALB (Homo sapiens)
BCHE hydrolyzes ASA- (Caenorhabditis elegans)
BCHE hydrolyzes ASA- (Drosophila melanogaster)
BCHE hydrolyzes ASA- (Gallus gallus)
BCHE hydrolyzes ASA- (Xenopus tropicalis)
BCHE hydrolyzes ASA- (Bos taurus)
BCHE hydrolyzes ASA- (Canis familiaris)
BCHE hydrolyzes ASA- (Rattus norvegicus)
BCHE hydrolyzes ASA- (Mus musculus)
BCHE hydrolyzes ASA- (Homo sapiens)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Caenorhabditis elegans)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Drosophila melanogaster)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Gallus gallus)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Xenopus tropicalis)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Danio rerio)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Sus scrofa)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Bos taurus)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Canis familiaris)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Rattus norvegicus)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Mus musculus)
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Homo sapiens)
as an output of
ASA- (GI) translocates from cytosol to extracellular region (Homo sapiens)
Acetylsalicylic acid dissolves (Homo sapiens)
as a member of
ASA-, ST [extracellular region]
MCT substrates [extracellular region]
Other forms of this molecule
ASA- (hepatocyte) [endoplasmic reticulum lumen]
ASA- (GI cell) [endoplasmic reticulum lumen]
ASA- (hepatocyte) [cytosol]
ASA- (GI cell) [cytosol]
ASA- [cytosol]
Cross References
ZINC
000000000053
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