WWTR1:p-2S-SMAD2,3:SMAD4 binds SERPINE1 gene promoter

Stable Identifier
R-HSA-9736959
Type
Reaction [binding]
Species
Homo sapiens
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By chromatin immunoprecipitation (ChIP) it was shown that both WWTR1 and the SMAD2,3:SMAD4 complex bind to the promoter of SERPINE1 gene in response to TGF-beta stimulation (Varelas et al. 2008).

Literature References
PubMed ID Title Journal Year
18568018 TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

Varelas, X, Sakuma, R, Samavarchi-Tehrani, P, Peerani, R, Rao, BM, Dembowy, J, Yaffe, MB, Zandstra, PW, Wrana, JL

Nat Cell Biol 2008
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