Miro GTPases are a separate family of Ras-related GTPases that are sometimes included in the atypical RHO GTPases group, but are phylogenetically distinct from the Rho family (Jaffe and Hall 2005; Boureux et al. 2007; Devine et al. 2016; Liu et al. 2017). Miro GTPases possess an additional GTPase domain more closely related to Rheb (Klosowiak et al. 2013). Miro family of RAS-like GTPases includes two members, RHOT1 and RHOT2. RHOT1 and RHOT2 regulate the movement of mitochondria (Schwarz 2013; Devine et al. 2016) and peroxisomes (Castro et al. 2018, Okumoto et al. 2018, Covill-Cooke et al. 2020).
Liu, WN, Yan, M, Chan, AM
Klosowiak, JL, Focia, PJ, Chakravarthy, S, Landahl, EC, Freymann, DM, Rice, SE
Schwarz, TL
Jaffe, AB, Hall, A
Castro, IG, Richards, DM, Metz, J, Costello, JL, Passmore, JB, Schrader, TA, Gouveia, A, Ribeiro, D, Schrader, M
Covill-Cooke, C, Toncheva, VS, Drew, J, Birsa, N, Lopez-Domenech, G, Kittler, JT
Boureux, A, Vignal, E, Faure, S, Fort, P
Devine, MJ, Birsa, N, Kittler, JT
Okumoto, K, Ono, T, Toyama, R, Shimomura, A, Nagata, A, Fujiki, Y
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