kinase domain ALK mutants [plasma membrane]

Stable Identifier
R-HSA-9700083
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
27432227 Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer

Gainor, JF, Dardaei, L, Yoda, S, Friboulet, L, Leshchiner, I, Katayama, R, Dagogo-Jack, I, Gadgeel, S, Schultz, K, Singh, M, Chin, E, Parks, M, Lee, D, DiCecca, RH, Lockerman, E, Huynh, T, Logan, J, Ritterhouse, LL, Le, LP, Muniappan, A, Digumarthy, S, Channick, C, Keyes, C, Getz, G, Dias-Santagata, D, Heist, RS, Lennerz, J, Sequist, LV, Benes, CH, Iafrate, AJ, Mino-Kenudson, M, Engelman, JA, Shaw, AT

Cancer Discov 2016
25421750 Treatment Efficacy and Resistance Mechanisms Using the Second-Generation ALK Inhibitor AP26113 in Human NPM-ALK-Positive Anaplastic Large Cell Lymphoma

Ceccon, M, Mologni, L, Giudici, G, Piazza, R, Pirola, A, Fontana, D, Gambacorti-Passerini, C

Mol. Cancer Res. 2015
20632993 Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain

Lee, CC, Jia, Y, Li, N, Sun, X, Ng, K, Ambing, E, Gao, MY, Hua, S, Chen, C, Kim, S, Michellys, PY, Lesley, SA, Harris, JL, Spraggon, G

Biochem. J. 2010
Participants
Participates
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
Mondo
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