FLT3 ITD- and STAT5-dependent CDKN1A gene expression

Stable Identifier
R-HSA-9698043
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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STAT5 binding to its cognate sites at positions -692 and -684 of the CDKN1a promoter leads to FLT3-dependent CDKN1A expression (Takahashi et al, 2004).

Literature References
PubMed ID Title Journal Year
15003515 Flt3 mutation activates p21WAF1/CIP1 gene expression through the action of STAT5

Takahashi, S, Harigae, H, Kaku, M, Sasaki, T, Licht, JD

Biochem. Biophys. Res. Commun. 2004
Participants
Participant Of
This event is regulated
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Authored
Reviewed
Created
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