CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 dissociates yielding CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and p-Y-STAT1,3,5

Stable Identifier
R-HSA-9674563
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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After phosphorylation while bound to phospho-CSF3R at the plasma membrane, p-STAT1,3,5 dissociates from CSF3R prior to dimerizing and transiting to the nucleus (Tian et al. 1994, Tian et al. 1996, Ward et al. 1999, also inferred from mouse homologs).

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