The AAA+ ATPase activity of spastin (SPAST) removes attached microtubules from chromosomes, allowing formation of a sealed nuclear envelope (Vietri et al. 2015, Ventimiglia et al. 2018).
Olmos, Y, Cuesta-Geijo, MA, Ventimiglia, LN, Carlton, JG, Miguet, N, Macheboeuf, P, Weissenhorn, W, Parnham, IM, Martinelli, N, Caballe, A, Martin-Serrano, J
Campsteijn, C, Schultz, SW, Schink, KO, Wegner, CS, Brech, A, Christ, L, Raiborg, C, Thoresen, SB, Stenmark, H, Vietri, M
microtubule-severing ATPase activity of LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope]
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