SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin

Stable Identifier
R-HSA-9668405
Type
Reaction [binding]
Species
Homo sapiens
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Spastin (SPAST), an AAA+ ATPase that severs microtubules attached to the chromosome surfaces, binds the ESCRT-III subunit IST1 (Vietri et al. 2015).

Literature References
PubMed ID Title Journal Year
26040712 Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing

Vietri, M, Schink, KO, Campsteijn, C, Wegner, CS, Schultz, SW, Christ, L, Thoresen, SB, Brech, A, Raiborg, C, Stenmark, H

Nature 2015
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