Reactome | CHMP7 binds CC2D1B

CHMP7 binds CC2D1B

Stable Identifier

R-HSA-9668395

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nuclear envelope

Locations in the PathwayBrowser

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Cell Cycle (Homo sapiens)

- Cell Cycle, Mitotic (Homo sapiens)
  - M Phase (Homo sapiens)
    - Mitotic Metaphase and Anaphase (Homo sapiens)
      - Mitotic Anaphase (Homo sapiens)
        
        Nuclear Envelope (NE) Reassembly (Homo sapiens)
        
        Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)
        
        CHMP7 binds CC2D1B (Homo sapiens)

General

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SVG | | PPTX | SBGN

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CHMP7 binding to CC2D1B temporally coordinates ESCRT-III assembly/disassembly with the microtubule severing activity of spastin (SPAST) (Ventimiglia et al. 2018).

Literature References

PubMed ID	Title	Journal	Year
30513301	CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope Ventimiglia, LN, Cuesta-Geijo, MA, Martinelli, N, Caballe, A, Macheboeuf, P, Miguet, N, Parnham, IM, Olmos, Y, Carlton, JG, Weissenhorn, W, Martin-Serrano, J	Dev. Cell	2018