Reactome | CHMP7 binds CC2D1B

CHMP7 binds CC2D1B

Stable Identifier

R-HSA-9668395

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nuclear envelope

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

Cell Cycle (Homo sapiens)

- Cell Cycle, Mitotic (Homo sapiens)
  - M Phase (Homo sapiens)
    - Mitotic Metaphase and Anaphase (Homo sapiens)
      - Mitotic Anaphase (Homo sapiens)
        
        Nuclear Envelope (NE) Reassembly (Homo sapiens)
        
        Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)
        
        CHMP7 binds CC2D1B (Homo sapiens)

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

CHMP7 binding to CC2D1B temporally coordinates ESCRT-III assembly/disassembly with the microtubule severing activity of spastin (SPAST) (Ventimiglia et al. 2018).

Literature References

PubMed ID	Title	Journal	Year
30513301	CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope Olmos, Y, Cuesta-Geijo, MA, Ventimiglia, LN, Carlton, JG, Miguet, N, Macheboeuf, P, Weissenhorn, W, Parnham, IM, Martinelli, N, Caballe, A, Martin-Serrano, J	Dev. Cell	2018