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CC2D1B [nuclear envelope]
Stable Identifier
R-HSA-9668424
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nuclear envelope
Synonyms
Coiled-coil and C2 domain-containing protein 1B, C2D1B_HUMAN
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)
CHMP7 binds CC2D1B (Homo sapiens)
CC2D1B [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
CC2D1B [nuclear envelope] (Homo sapiens)
SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
CC2D1B [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
CC2D1B [nuclear envelope] (Homo sapiens)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
CC2D1B [nuclear envelope] (Homo sapiens)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
CC2D1B [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
CC2D1B [nuclear envelope] (Homo sapiens)
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
CC2D1B [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
CC2D1B [nuclear envelope] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5T0F9 CC2D1B
Gene Names
CC2D1B, KIAA1836, LGD1
Chain
chain:1-858
Reference Genes
BioGPS Gene:200014 CC2D1B
COSMIC (genes):CC2D1B CC2D1B
CTD Gene:200014 CC2D1B
dbSNP Gene:200014 CC2D1B
ENSEMBL:ENSG00000154222 CC2D1B
HGNC:29386 CC2D1B
KEGG:hsa:200014 CC2D1B
Monarch:200014 CC2D1B
NCBI Gene:200014 CC2D1B
UCSC:Q5T0F9 CC2D1B
Reference Transcript
RefSeq:NM_001330585.1 CC2D1B
RefSeq:NM_032449.2 CC2D1B
RefSeq:XM_005270590.2 CC2D1B
Other Identifiers
11733847_a_at
11733848_at
16687150
200014
225323_PM_at
225323_at
237337_PM_at
237337_at
2412741
2412743
2412744
2412745
2412746
2412747
2412748
2412749
2412750
2412751
2412752
2412753
2412754
2412755
2412756
2412757
2412758
2412759
2412760
2412761
2412762
2412763
2412764
2412765
2412766
2412767
2412768
2412769
2412771
2412773
2412774
2412775
2412776
2412777
2412778
2412779
2412780
2412781
2412782
2412783
2412784
2412787
2412790
2412791
2412792
242487_PM_at
242487_at
43361_s_at
53146_at
74137_at
75700_at
7916135
A_23_P383031
A_24_P76740
A_33_P3247180
A_33_P3247190
GE797567
GE898766
GO:0000122
GO:0000978
GO:0000981
GO:0001227
GO:0003677
GO:0005515
GO:0005634
GO:0005635
GO:0005654
GO:0005829
GO:0006355
GO:0006357
GO:0010008
GO:0043226
GO:0043231
GO:0140110
HMNXSV003042177
HMNXSV003058271
Hs.115580.0.A1_3p_at
Hs.250953.0.A1_3p_at
Hs.318773.0.A1_3p_at
ILMN_1690291
ILMN_2149935
PH_hs_0016001
TC01002657.hg
TC01005488.hg
Participates
as an input of
CHMP7 binds CC2D1B (Homo sapiens)
as an output of
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
as a component of
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
Inferred To
Cc2d1b [nuclear envelope]
(Mus musculus)
Cc2d1b [nuclear envelope]
(Rattus norvegicus)
cc2d1b [nuclear envelope]
(Danio rerio)
cc2d1b [nuclear envelope]
(Xenopus tropicalis)
l(2)gd1 [nuclear envelope]
(Drosophila melanogaster)
CC2D1B [nuclear envelope]
(Bos taurus)
CC2D1B [nuclear envelope]
(Caenorhabditis elegans)
CC2D1B [nuclear envelope]
(Canis familiaris)
CC2D1B [nuclear envelope]
(Dictyostelium discoideum)
CC2D1B [nuclear envelope]
(Gallus gallus)
CC2D1B [nuclear envelope]
(Sus scrofa)
Ghost homologue of CC2D1B [nuclear envelope]
(Saccharomyces cerevisiae)
Ghost homologue of CC2D1B [nuclear envelope]
(Schizosaccharomyces pombe)
Cross References
ENSEMBL
ENSG00000154222
,
ENST00000284376
,
ENSP00000284376
,
ENSP00000360642
,
ENST00000371586
OpenTargets
ENSG00000154222
GeneCards
CC2D1B
HPA
ENSG00000154222-CC2D1B
PRO
Q5T0F9
Pharos - Targets
Q5T0F9
GlyGen
Q5T0F9
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99750 MDFI
0.556
3
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