OXGR1 binds 2OG

Stable Identifier
R-HSA-964773
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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OXGR1 binds 2OG
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Originally described as GPR80 and classified as a purinergic receptor, OXGR1 has now been shown to bind 2-oxoglutarate (2OG, alpha-ketoglutarate).

Literature References
PubMed ID Title Journal Year
15141213 Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors

Lin, DC, Miao, FJ, Ling, L, Wang, Z, Gao, J, Schwandner, RT, Chen, JL, He, W, Tian, H

Nature 2004
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Orthologous Events
OXGR1 binds 2OG (Bos taurus)
OXGR1 binds 2OG (Canis familiaris)
OXGR1 binds 2OG (Danio rerio)
OXGR1 binds 2OG (Gallus gallus)
OXGR1 binds 2OG (Mus musculus)
OXGR1 binds 2OG (Rattus norvegicus)
Authored
Jupe, S  (2010-09-10)
Reviewed
D'Eustachio, P  (2013-05-17)
Created
Jupe, S  (2010-09-17)
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