Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
p14ARF translocates to the nucleus
Stable Identifier
R-HSA-9645672
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
,
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Oncogene Induced Senescence (Homo sapiens)
p14ARF translocates to the nucleus (Homo sapiens)
Oxidative Stress Induced Senescence (Homo sapiens)
p14ARF translocates to the nucleus (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
Click the image above or
here
to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
p14ARF is mainly localized inside the nucleus, specifically the nucleolus (Zhang and Xiong 1999, Lindstrom et al. 2000), similar to its mouse orthologue p19ARF (Tao and Levine 1999).
Literature References
PubMed ID
Title
Journal
Year
10772813
Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus
Klangby, U
,
Lindström, MS
,
Inoue, R
,
Wiman, KG
,
Pisa, P
,
Asker, CE
Exp. Cell Res.
2000
Participants
Input
p14ARF [cytosol]
(Homo sapiens)
Output
p14ARF [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Oxidative Stress Induced Senescence (Homo sapiens)
Oncogene Induced Senescence (Homo sapiens)
Authored
Orlic-Milacic, M (2019-06-28)
Reviewed
Rizos, H (2019-07-08)
Bennett, DC (2019-08-12)
Created
Orlic-Milacic, M (2019-05-17)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text