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WDR24 [lysosomal membrane]
Stable Identifier
R-HSA-9638247
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
fullName evidence="16"GATOR complex protein WDR24, WDR24_HUMAN
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Amino acids regulate mTORC1 (Homo sapiens)
CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
RRAGA,B hydrolyzes GTP (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
SESN1,2 binds L-leucine and dissociates from GATOR2 (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
WDR24 [lysosomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96S15 WDR24
Gene Names
WDR24, C16orf21, JFP7
Chain
chain:1-790
Reference Genes
BioGPS Gene:84219 WDR24
COSMIC (genes):WDR24 WDR24
CTD Gene:84219 WDR24
dbSNP Gene:84219 WDR24
ENSEMBL:ENSG00000127580 WDR24
HGNC:20852 WDR24
KEGG:hsa:84219 WDR24
Monarch:84219 WDR24
NCBI Gene:84219 WDR24
OMIM:620307 WDR24
UCSC:Q96S15 WDR24
Reference Transcript
RefSeq:NM_032259.3 WDR24
Other Identifiers
11722885_at
11747696_a_at
16822478
16822490
223293_PM_at
223293_at
3675275
3675276
3675277
3675278
3675279
3675280
3675281
3675282
3675283
3675284
3675286
3675287
3675288
3675289
3675290
3675291
3675292
3675293
3675294
3675295
3675296
3675297
3675299
3675300
3675301
3675302
3675303
3675304
3675305
3675306
3675307
48491_at
68512_at
7998267
7998280
84219
A_23_P26476
A_33_P3248759
A_33_P3373850
GE79145
GO:0003824
GO:0005515
GO:0005764
GO:0005765
GO:0005773
GO:0005774
GO:0005829
GO:0006914
GO:0010506
GO:0016020
GO:0016239
GO:0016567
GO:0016740
GO:0031669
GO:0032008
GO:0034198
GO:0043226
GO:0043231
GO:0046872
GO:0061630
GO:0061700
GO:0085020
GO:0140096
GO:1904262
GO:1904263
HMNXSV003001193
HMNXSV003002455
ILMN_1761442
PH_hs_0006119
TC16000735.hg
g12053230_3p_at
Participates
as a component of
GATOR2 [lysosomal membrane] (Homo sapiens)
Inferred To
Q54JS5 [lysosomal membrane]
(Dictyostelium discoideum)
Q5ZMV9 [lysosomal membrane]
(Gallus gallus)
Wdr24 [lysosomal membrane]
(Rattus norvegicus)
WDR24 [lysosomal membrane]
(Bos taurus)
WDR24 [lysosomal membrane]
(Canis familiaris)
WDR24 [lysosomal membrane]
(Sus scrofa)
Q8CFJ9 [lysosomal membrane]
(Mus musculus)
wdr24 [lysosomal membrane]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENST00000293883
,
ENSP00000293883
,
ENSG00000127580
OpenTargets
ENSG00000127580
GeneCards
WDR24
HPA
ENSG00000127580-WDR24
PRO
Q96S15
Pharos - Targets
Q96S15
PDB
7UHY
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P55735 SEC13
4
SEC13 [cytosol]
(R-HSA-203981)
SEC13 [endoplasmic reticulum membrane]
(R-HSA-203994)
SEC13 [ER to Golgi transport vesicle membrane]
(R-HSA-204012)
SEC13 [lysosomal membrane]
(R-HSA-9638246)
0.725
7
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