Manipulation of host energy metabolism

Stable Identifier
R-HSA-9636667
Type
Pathway
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
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Mtb secretes proteins that enhance enzymatic activity of glucose metabolism in the phagocyte. The same proteins also appear to increase glucose uptake and to cause accumulation of DHAP, ultimately increasing the host cell's lipid production (Singh et al. 2015).

Literature References
PubMed ID Title Journal Year
26250836 M. tuberculosis Secretory Protein ESAT-6 Induces Metabolic Flux Perturbations to Drive Foamy Macrophage Differentiation

Singh, V, Kaur, C, Chaudhary, VK, Rao, KV, Chatterjee, S

Sci Rep 2015
Participants
Participant Of
Event Information
Disease
Name Identifier Synonyms
tuberculosis 399 tuberculous abscess, Tuberculoma (finding), tuberculoma
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