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EsxA binds ENO1
Stable Identifier
R-HSA-9636669
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Response of Mtb to phagocytosis (Homo sapiens)
Manipulation of host energy metabolism (Homo sapiens)
EsxA binds ENO1 (Homo sapiens)
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Mtb secreted 6 kDa early secretory antigenic target (EsxA) binds to human enolase-1 protein (ENO1) (Singh et al. 2015).
Literature References
PubMed ID
Title
Journal
Year
26250836
M. tuberculosis Secretory Protein ESAT-6 Induces Metabolic Flux Perturbations to Drive Foamy Macrophage Differentiation
Rao, KV
,
Kaur, C
,
Chatterjee, S
,
Chaudhary, VK
,
Singh, V
Sci Rep
2015
Participants
Input
ENO1 [cytosol]
(Homo sapiens)
EsxA [cytosol]
(Mycobacterium tuberculosis)
Output
EsxA:ENO1 [cytosol]
(Homo sapiens)
Participates
as an event of
Manipulation of host energy metabolism (Homo sapiens)
Disease
Name
Identifier
Synonyms
tuberculosis
DOID:399
tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R (2019-02-06)
Reviewed
Wilkinson, RJ (2019-10-23)
Deffur, A (2019-10-23)
Created
Pardo, AM (2019-02-13)
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