LAM translocates from the cell wall to the plasma membrane

Stable Identifier
R-HSA-9636404
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
peptidoglycan-based cell wall, plasma membrane
ReviewStatus
5/5
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LAM translocates from the cell wall to the plasma membrane
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Lipoarabinomannan (LAM) is shedded from Mtb's outer cell wall into the phagocyte's plasma membrane (Welin et al. 2008).
Literature References
PubMed ID Title Journal Year
18426888 Incorporation of Mycobacterium tuberculosis lipoarabinomannan into macrophage membrane rafts is a prerequisite for the phagosomal maturation block

Abdalla, H, Winberg, ME, Lerm, M, Rasmusson, B, Welin, A, Stendahl, O, Särndahl, E

Infect. Immun. 2008
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-06)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Koile, I  (2019-02-13)
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