PtpA binds ATP6V1H

Stable Identifier
R-HSA-9636397
Type
Reaction
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
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PtpA binds ATP6V1H
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The H subunit of human cytosolic ATPase (ATP6V1H) binds to the Mtb probable low molecular weight protein-tyrosine phosphatase (ptpA), directly impairing ATPase trafficking to the phagosome (Wong et al. 2011).

Literature References
PubMed ID Title Journal Year
22087003 Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification

Hmama, Z, Sun, J, Av-Gay, Y, Bach, H, Wong, D

Proc. Natl. Acad. Sci. U.S.A. 2011
Participants
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Output
Participates
as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-06)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Koile, I  (2019-02-13)
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