SecA2 transports SapM from cytoplasm to cytosol

Stable Identifier
R-HSA-9636375
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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SecA2 transports SapM from cytoplasm to cytosol
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Mtb protein translocase subunit (SecA2) transports phosphatidylinositol-3-phosphatase (SapM) from Mtb's cytosol (called cytoplasm here) to the host's cytosol (Zulauf et al. 2018).
Literature References
PubMed ID Title Journal Year
29709019 The SecA2 pathway of Mycobacterium tuberculosis exports effectors that work in concert to arrest phagosome and autophagosome maturation

Zulauf, KE, Sullivan, JT, Braunstein, M

PLoS Pathog. 2018
Participants
Input
Output
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as an event of
Catalyst Activity

protein transmembrane transporter activity of SecA2 [plasma membrane]

Physical Entity
SecA2 [plasma membrane] (Mycobacterium tuberculosis H37Rv)
Activity
protein transmembrane transporter activity (GO:0008320)
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Cross References
Mondo
Authored
Stephan, R  (2019-02-06)
Reviewed
Deffur, A  (2019-10-23)
Wilkinson, RJ  (2019-10-23)
Created
Koile, I  (2019-02-13)
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