SecA2 transports SapM from cytoplasm to cytosol

Stable Identifier
R-HSA-9636375
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
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Mtb protein translocase subunit (SecA2) transports phosphatidylinositol-3-phosphatase (SapM) from Mtb's cytosol (called cytoplasm here) to the host's cytosol (Zulauf et al. 2018).

Literature References
PubMed ID Title Journal Year
29709019 The SecA2 pathway of Mycobacterium tuberculosis exports effectors that work in concert to arrest phagosome and autophagosome maturation

Zulauf, KE, Sullivan, JT, Braunstein, M

PLoS Pathog. 2018
Participants
Participates
Catalyst Activity

protein transmembrane transporter activity of secA2 [plasma membrane]

Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Reviewed
Created
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