PPE2 binds NOS2 gene

Stable Identifier
R-HSA-9636240
Type
Reaction
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
nucleoplasm
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PPE2 binds NOS2 gene
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PPE famly protein PPE2 binds to regulatory elements of the inducible nitric oxide synthase (NOS2) gene which is important for NOS2 gene transcription (Bhat 2017).

Literature References
PubMed ID Title Journal Year
28071726 The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production

Ghosh, S, Mukhopadhyay, S, Kotturu, SK, Bhat, KH, Srivastava, S

Sci Rep 2017
Participants
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Output
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as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-06)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Koile, I  (2019-02-12)
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