CDK5 gene expression is stimulated by NPAS4

Stable Identifier
R-HSA-9634916
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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CDK5 gene expression is stimulated by NPAS4
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Based on studies in mouse, NPAS4 directly stimulates expression of the CDK5 gene, encoding cyclin-dependent-like kinase 5 (Yun et al. 2013), a serine/threonine protein kinase which is essential for neuronal cell cycle exit and differentiation.
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
(NPAS4:ARNTL,NPAS4:ARNT,NPAS4:ARNT2):CDK5 gene [nucleoplasm] (Homo sapiens)
Active Unit
(NPAS4:ARNTL,NPAS4:ARNT,NPAS4:ARNT2) [nucleoplasm]
Inferred From
Cdk5 gene expression is stimulated by Npas4 (Mus musculus)
Authored
Orlic-Milacic, M  (2022-04-08)
Reviewed
Lin, Y  (2022-07-29)
Created
Orlic-Milacic, M  (2019-01-16)
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