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NUP93 recruits the Nup62 complex
Stable Identifier
R-HSA-9634219
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nuclear envelope
,
cytosol
ReviewStatus
5/5
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Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Postmitotic nuclear pore complex (NPC) reformation (Homo sapiens)
NUP93 recruits the Nup62 complex (Homo sapiens)
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The N-terminal domain of NUP93, the eponymous subunit of the Nup93 complex, recruits the Nup62 complex, consisting of phenylglycine (FG) repeat-containing nucleoporins NUP62, NUP58 and NUP54 (Chug et al. 2015), to the nascent nuclear pore complex (NPC) (Sachdev et al. 2012). The barrier function of the NPC is reestablished at this point (Dultz et al. 2008).
Participants
Input
x 32
Nup62 Complex [cytosol]
(Homo sapiens)
Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin [nuclear envelope]
(Homo sapiens)
Output
Nup62 complex:Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin [nuclear envelope]
(Homo sapiens)
Participates
as an event of
Postmitotic nuclear pore complex (NPC) reformation (Homo sapiens)
Inferred From
Nup93 binds Nup62 complex (Xenopus laevis)
Authored
Gerace, L (2019-11-07)
Created
Orlic-Milacic, M (2019-01-08)
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