KAT2B,EP300 acetylate FOXO3 under oxidative stress

Stable Identifier
R-HSA-9620515
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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KAT2B (PCAF) and possibly EP300 (p300) acetylate FOXO3 under conditions of oxidative stress (Brunet et al. 2004).

Literature References
PubMed ID Title Journal Year
14976264 Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

Brunet, A, Sweeney, LB, Sturgill, JF, Chua, KF, Greer, PL, Lin, Y, Tran, H, Ross, SE, Mostoslavsky, R, Cohen, HY, Hu, LS, Cheng, HL, Jedrychowski, MP, Gygi, SP, Sinclair, DA, Alt, FW, Greenberg, ME

Science 2004
Participants
Participates
Catalyst Activity

peptide-lysine-N-acetyltransferase activity of KAT2B,(EP300) [nucleoplasm]

This event is regulated
Positively by
Regulator
Orthologous Events
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