CAMK1 binds calmodulin

Stable Identifier
R-HSA-9619376
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Activated calmodulin (CALM1:4xCa2+) binds to the C-terminal region of CAMK1 (CaMKI). Calmodulin binding exposes CaMKK target site, threonine T177, on CAMK1 (Haribabu et al. 1995).

Literature References
PubMed ID Title Journal Year
7641687 Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase

Haribabu, B, Hook, SS, Selbert, MA, Goldstein, EG, Tomhave, ED, Edelman, AM, Snyderman, R, Means, AR

EMBO J. 1995
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created