MIR137 gene expression is inhibited by MECP2 and SOX2

Stable Identifier
R-HSA-9615554
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
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MIR137 gene expression is inhibited by MECP2 and SOX2
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Based on studies in mouse neurons, MECP2 and SOX2 directly repress transcription from the MIR137 gene, encoding microRNA miR-137 (Szulwach et al. 2010, Lyu et al. 2016).

Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
MECP2:SOX2:MIR137 gene [nucleoplasm] (Homo sapiens)
Active Unit
SOX2 [nucleoplasm]
MECP2 [nucleoplasm]
Inferred From
Mir137 gene expression is inhibited by Mecp2 and Sox2 (Mus musculus)
Authored
Orlic-Milacic, M  (2018-08-08)
Reviewed
Krishnaraj, R  (2018-08-07)
Christodoulou, J  (2018-08-07)
Created
Orlic-Milacic, M  (2018-08-07)
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