MIR132 gene expression is stimulated by p-S133-CREB1

Stable Identifier
R-HSA-9615501
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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MIR132 gene expression is stimulated by p-S133-CREB1
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Based on studies in rat and mouse cells, CREB1 induces transcription of the MIR132 gene, encoding miR-132 microRNA (Vo et al. 2005, Lyu et al. 2016). Activation of CREB1 by phosphorylation at serine residue S133 in response to PTEN knockdown results in increased levels of miR-132 (Lyu et al. 2016).
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
p-S133-CREB1:MIR132 gene [nucleoplasm] (Homo sapiens)
Active Unit
p-S133-CREB1 homodimer [nucleoplasm]
Inferred From
Mir132 gene expression is stimulated by p-S133-Creb1 (Rattus norvegicus)
Authored
Orlic-Milacic, M  (2018-08-08)
Reviewed
Krishnaraj, R  (2018-08-07)
Christodoulou, J  (2018-08-07)
Created
Orlic-Milacic, M  (2018-08-07)
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