Reactome | Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A)

Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A)

Stable Identifier

R-HSA-9609743

Type

Reaction [binding]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

ReviewStatus

5/5

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Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A)

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GluN1 (GRIN1) binds to GluN2B (GRIN2B) and GluN3A (GRIN3A) to form a tri-heteromeric NMDA receptor GluN1:GluN2B:GluN3A (GRIN1:GRIN2B:GRIN3A) (Das et al. 1998, Al-Hallaq et al. 2002, Nilsson et al. 2007).

Literature References

PubMed ID	Title	Journal	Year
17997397	Analysis of NR3A receptor subunits in human native NMDA receptors Nilsson, A, Eriksson, M, Muly, EC, Akesson, E, Samuelsson, EB, Bogdanovic, N, Benedikz, E, Sundström, E	Brain Res.	2007