Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GRIN3A [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-9609764
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Glutamate (NMDA) receptor subunit 3A, NR3A
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Assembly and cell surface presentation of NMDA receptors (Homo sapiens)
Formation of di-heterotetramers of GluN1 (GRIN1) and GluN3A (GRIN3A) (Homo sapiens)
GRIN1:GRIN3A di-heterotetramer [endoplasmic reticulum membrane] (Homo sapiens)
GRIN3A [endoplasmic reticulum membrane] (Homo sapiens)
GRIN3A [endoplasmic reticulum membrane] (Homo sapiens)
Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN3A (GRIN3A) (Homo sapiens)
GRIN1:GRIN2A:GRIN3A tri-heterotetramer [endoplasmic reticulum membrane] (Homo sapiens)
GRIN3A [endoplasmic reticulum membrane] (Homo sapiens)
GRIN3A [endoplasmic reticulum membrane] (Homo sapiens)
Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A) (Homo sapiens)
GRIN1:GRIN2B:GRIN3A tri-heterotetramer [endoplasmic reticulum membrane] (Homo sapiens)
GRIN3A [endoplasmic reticulum membrane] (Homo sapiens)
GRIN3A [endoplasmic reticulum membrane] (Homo sapiens)
GluN3A (GRIN3A), GluN3B (GRIN3B) NMDA receptors traffic to the plasma membrane (Homo sapiens)
GRIN1:GRIN3 di-heteromers,(GRIN1:GRIN2:GRIN3 tri-heteromers) [endoplasmic reticulum membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN3A tri-heterotetramer [endoplasmic reticulum membrane] (Homo sapiens)
GRIN3A [endoplasmic reticulum membrane] (Homo sapiens)
GRIN1:GRIN2B:GRIN3A tri-heterotetramer [endoplasmic reticulum membrane] (Homo sapiens)
GRIN3A [endoplasmic reticulum membrane] (Homo sapiens)
GRIN1:GRIN3A di-heterotetramer [endoplasmic reticulum membrane] (Homo sapiens)
GRIN3A [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TCU5 GRIN3A
Gene Names
GRIN3A, KIAA1973
Chain
signal peptide:1-23, chain:24-1115
Reference Genes
BioGPS Gene:116443 GRIN3A
COSMIC (genes):GRIN3A GRIN3A
CTD Gene:116443 GRIN3A
dbSNP Gene:116443 GRIN3A
ENSEMBL:ENSG00000198785 GRIN3A
HGNC:16767 GRIN3A
KEGG:hsa:116443 GRIN3A
Monarch:116443 GRIN3A
NCBI Gene:116443 GRIN3A
OMIM:606650 GRIN3A
UCSC:Q8TCU5 GRIN3A
Reference Transcript
RefSeq:NM_133445.2 GRIN3A
Other Identifiers
116443
11732761_a_at
11732762_at
11732763_at
17096669
233171_PM_at
233171_at
233220_PM_at
233220_at
3218152
3218153
3218154
3218155
3218156
3218157
3218158
3218159
3218160
3218165
3218166
3218168
3218169
3218171
3218174
3218175
3218176
3218183
3218184
3218185
3218193
3218194
3218195
3218196
3218216
48885_at
8162908
A_23_P347541
GE56707
GE80500
GO:0004970
GO:0004972
GO:0005215
GO:0005216
GO:0005262
GO:0005515
GO:0005737
GO:0005789
GO:0005886
GO:0006811
GO:0006816
GO:0007215
GO:0008066
GO:0014069
GO:0015276
GO:0016020
GO:0016358
GO:0016594
GO:0017146
GO:0022824
GO:0023052
GO:0031090
GO:0034220
GO:0035235
GO:0035249
GO:0038023
GO:0042802
GO:0043005
GO:0043025
GO:0043226
GO:0045202
GO:0045211
GO:0045471
GO:0048511
GO:0048666
GO:0048856
GO:0050804
GO:0051721
GO:0055085
GO:0060078
GO:0060089
GO:0060134
GO:0061000
GO:0070588
GO:0098793
GO:0098839
GO:0098978
GO:0099171
GO:1904315
HMNXSV003034382
Hs.26849.0.S1_3p_at
Hs.283852.0.S1_3p_at
Hs.283852.0.S1_3p_x_at
ILMN_1758400
PH_hs_0014690
TC09001423.hg
Participates
as an input of
Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN3A (GRIN3A) (Homo sapiens)
Formation of di-heterotetramers of GluN1 (GRIN1) and GluN3A (GRIN3A) (Homo sapiens)
Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A) (Homo sapiens)
as a component of
GRIN1:GRIN3A di-heterotetramer [endoplasmic reticulum membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN3A tri-heterotetramer [endoplasmic reticulum membrane] (Homo sapiens)
GRIN1:GRIN2B:GRIN3A tri-heterotetramer [endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
GRIN3A [plasma membrane]
Inferred To
grin3a [endoplasmic reticulum membrane]
(Xenopus tropicalis)
Grin3a [endoplasmic reticulum membrane]
(Mus musculus)
Grin3a [endoplasmic reticulum membrane]
(Rattus norvegicus)
GRIN3A [endoplasmic reticulum membrane]
(Canis familiaris)
GRIN3A [endoplasmic reticulum membrane]
(Gallus gallus)
GRIN3A [endoplasmic reticulum membrane]
(Sus scrofa)
Cross References
RefSeq
NP_597702.2
Guide to Pharmacology - Targets
460
ENSEMBL
ENSP00000355155
,
ENST00000361820
OpenTargets
ENSG00000198785
HPA
ENSG00000198785-GRIN3A
PRO
Q8TCU5
Pharos - Targets
Q8TCU5
GlyGen
Q8TCU5
HMDB Protein
HMDBP07845
PDB
8UUE
,
8USW
,
8USX
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text