PEX19 binds PEX3

Stable Identifier
R-HSA-9603801
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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In the cytosol, PEX19 binds to newly translated PEX3 (inferred from human PEX19 binding rat Pex3). PEX19 binds the C-terminal region of PEX3 and the membrane targeting signal of PEX3 is located in the N-terminal region (Soukupova et al. 1999, Fransen et al. 2001, Fransen et al. 2005).

Literature References
PubMed ID Title Journal Year
10430017 Identification and characterization of the human peroxin PEX3

Soukupova, M, Sprenger, C, Gorgas, K, Kunau, WH, Dodt, G

Eur. J. Cell Biol. 1999
11390669 Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences

Fransen, M, Wylin, T, Brees, C, Mannaerts, GP, Van Veldhoven, PP

Mol. Cell. Biol. 2001
15713480 Analysis of human Pex19p's domain structure by pentapeptide scanning mutagenesis

Fransen, M, Vastiau, I, Brees, C, Brys, V, Mannaerts, GP, Van Veldhoven, PP

J. Mol. Biol. 2005
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