p-IRF7 dimer interacts with coactivator CBP/p300

Stable Identifier
R-HSA-933536
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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p-IRF7 dimer interacts with coactivator CBP/p300
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p-IRF7 dimers after translocation into nucleus interact with the coactivators p300 and CBP (CREB-binding protein) to form a stable complex. This interaction further increases the transcriptional activity of IRF7.

Literature References
PubMed ID Title Journal Year
12604599 Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators

Yang, H, Lin, CH, Ma, G, Baffi, MO, Wathelet, MG

J Biol Chem 2003
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Orthologous Events
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p-IRF7 dimer interacts with coactivator CBP/p300 (Rattus norvegicus)
p-IRF7 dimer interacts with coactivator CBP/p300 (Sus scrofa)
p-IRF7 dimer interacts with coactivator CBP/p300 (Xenopus tropicalis)
Authored
Garapati, P V  (2010-08-02)
Reviewed
Kawai, T  (2010-10-30)
Akira, S  (2010-10-30)
Created
Garapati, P V  (2010-08-16)
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