Sulfido conjugates translocate from cytosol to extracellular region

Stable Identifier
R-HSA-9031856
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
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To produce their pro-resolving effects, DHA-derived sulfido conjugates (MCTR1-3, PCTR1-3 and RCTR1-3) are released into the exudate of local inflammation sites (Dalli et al. 2015, 2016). The mechanism of translocation is unknown.

Literature References
PubMed ID Title Journal Year
25713027 Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways

Dalli, J, Ramon, S, Norris, PC, Colas, RA, Serhan, CN

FASEB J. 2015
27791009 Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

Dalli, J, Vlasakov, I, Riley, IR, Rodriguez, AR, Spur, BW, Petasis, NA, Chiang, N, Serhan, CN

Proc. Natl. Acad. Sci. U.S.A. 2016
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