BDNF-bound NTRK2 dimerizes

Stable Identifier
R-HSA-9024967
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
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BDNF-bound NTRK2 dimerizes
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Based on studies in macaque monkeys, BDNF binding induces dimerization of the NTRK2 (TRKB) receptor (Ohira et al. 2001). The existence of preformed, BDNF-independent, dimers of NTRK2 was demonstrated when NTRK2 was overexpressed from an exogenous vector (Shen and Maruyama).

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Input
Output
Participant Of
hasEvent
Inferred From
BDNF-bound Ntrk2 dimerizes (Macaca mulatta)
Authored
Orlic-Milacic, M  (2018-01-05)
Reviewed
Antila, H  (2018-02-13)
Castrén, E  (2018-02-13)
Created
Orlic-Milacic, M  (2017-10-11)