In its active GTP bound form, RHOV binds the following effectors:PAK2 (Aronheim et al. 1998; Bagci et al. 2020)PAK6 (Shepelev and Korobko 2012)The following candidate RHOV effectors were identified in the high throughput screen by Bagci et al. 2020:ARHGAP12 (Bagci et al. 2020)ARHGEF7 (Bagci et al. 2020)CCP110 (Bagci et al. 2020)CDC42 (Bagci et al. 2020)CEP97 (Bagci et al. 2020)CLTC (Bagci et al. 2020)DEPDC1B (Bagci et al. 2020)DLG5 (Bagci et al. 2020)DST (Bagci et al. 2020)EPHA2 (Bagci et al. 2020)GIT1 (Bagci et al. 2020)GIT2 (Bagci et al. 2020)IQGAP1 (Bagci et al. 2020)MAP3K21 (Bagci et al. 2020)MYH11 (Bagci et al. 2020)MYL12B (Bagci et al. 2020)MYO6 (Bagci et al. 2020)MYO9A (Bagci et al. 2020)NCK1 (Bagci et al. 2020)NCK2 (Bagci et al. 2020);PAK1 (Bagci et al. 2020)PEAK1 (Bagci et al. 2020)PIK3R1 (Bagci et al. 2020)SH3RF1 (Bagci et al. 2020)SPTAN1 (Bagci et al. 2020)SPTBN1 (Bagci et al. 2020)TPM3 (Bagci et al. 2020)TPM4 (Bagci et al. 2020)TXNL1 (Bagci et al. 2020)USP9X (Bagci et al. 2020)VANGL1 (Bagci et al. 2020)WASL (Bagci et al. 2020)WDR6 (Bagci et al. 2020)ZNF512B (Bagci et al. 2020)Active RHOV does not bind the following putative effector proteins which do bind active RHOU:HGS (Bagci et al. 2020)PAK3 (Bagci et al. 2020)STAM (Bagci et al. 2020)STAM2 (Bagci et al. 2020)WWP2 (Bagci et al. 2020)
Bagci, H, Sriskandarajah, N, Robert, A, Boulais, J, Elkholi, IE, Tran, V, Lin, ZY, Thibault, MP, Dubé, N, Faubert, D, Hipfner, DR, Gingras, AC, Cote, JF
Aronheim, A, Broder, YC, Cohen, A, Fritsch, A, Belisle, B, Abo, A
Shepelev, MV, Korobko, IV
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