RUNX2-P2 binds RUNX2 gene promoter

Stable Identifier
R-HSA-9016526
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RUNX2-P2 binds RUNX2 gene promoter
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Based on studies in mice, RUNX2-P2 (RUNX2 variant expressed from the proximal promoter) binds to RUNX2 response elements in the proximal P2 promoter of the RUNX2 gene (Ducy et al. 1999). It is assumed that RUNX2 is associated with at least CBFB and the RUNX2 promoter, although this has not been examined.
Literature References
PubMed ID Title Journal Year
10215629 A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development

Ducy, P, Starbuck, M, Priemel, M, Shen, J, Pinero, G, Geoffroy, V, Amling, M, Karsenty, G

Genes Dev. 1999
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Runx2-P2 binds to Runx2 gene promoter (Mus musculus)
Authored
Orlic-Milacic, M  (2017-08-14)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2017-08-14)
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