Reactome | RAC2 translocates to the phagocytic vesicle membrane

RAC2 translocates to the phagocytic vesicle membrane

Stable Identifier

R-HSA-9014420

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

plasma membrane, phagocytic vesicle membrane

ReviewStatus

5/5

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RAC2 translocates to the phagocytic vesicle membrane

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RAC2 is able to translocate from the plasma membrane compartment to the phagocytic vesicle membrane (Hoppe and Swanson 2004; Ueyama et al. 2005; Faure et al. 2013).

Literature References

PubMed ID	Title	Journal	Year
23870057	The recruitment of p47(phox) and Rac2G12V at the phagosome is transient and phosphatidylserine dependent Dupré-Crochet, S, Tschirhart, E, Delattre, M, Melchior, C, Prigent, M, Cuif, MH, Nüsse, O, Sulpice, JC, Faure, MC, Lavielle, M	Biol. Cell	2013
15169870	Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis Swanson, JA, Hoppe, AD	Mol Biol Cell	2004
16081809	Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome Takeya, R, Lennartz, MR, Saito, N, Sumimoto, H, Eto, M, Tatsuno, T, Kami, K, Shirai, Y, Kobayashi, T, Ueyama, T	J. Immunol.	2005