RAC2 translocates to the phagocytic vesicle membrane

Stable Identifier
R-HSA-9014420
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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RAC2 is able to translocate from the plasma membrane compartment to the phagocytic vesicle membrane (Hoppe and Swanson 2004; Ueyama et al. 2005; Faure et al. 2013).

Literature References
PubMed ID Title Journal Year
15169870 Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis

Hoppe, AD, Swanson, JA

Mol Biol Cell 2004
23870057 The recruitment of p47(phox) and Rac2G12V at the phagosome is transient and phosphatidylserine dependent

Faure, MC, Sulpice, JC, Delattre, M, Lavielle, M, Prigent, M, Cuif, MH, Melchior, C, Tschirhart, E, Nüsse, O, Dupré-Crochet, S

Biol. Cell 2013
16081809 Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome

Ueyama, T, Eto, M, Kami, K, Tatsuno, T, Kobayashi, T, Shirai, Y, Lennartz, MR, Takeya, R, Sumimoto, H, Saito, N

J. Immunol. 2005
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