Reactome | RAC2 translocates to the phagocytic vesicle membrane

RAC2 translocates to the phagocytic vesicle membrane

Stable Identifier

R-HSA-9014420

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

plasma membrane, phagocytic vesicle membrane

ReviewStatus

5/5

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RAC2 translocates to the phagocytic vesicle membrane

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RAC2 is able to translocate from the plasma membrane compartment to the phagocytic vesicle membrane (Hoppe and Swanson 2004; Ueyama et al. 2005; Faure et al. 2013).

Literature References

PubMed ID	Title	Journal	Year
23870057	The recruitment of p47(phox) and Rac2G12V at the phagosome is transient and phosphatidylserine dependent Faure, MC, Sulpice, JC, Delattre, M, Lavielle, M, Prigent, M, Cuif, MH, Melchior, C, Tschirhart, E, Nüsse, O, Dupré-Crochet, S	Biol. Cell	2013
15169870	Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis Hoppe, AD, Swanson, JA	Mol Biol Cell	2004
16081809	Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome Ueyama, T, Eto, M, Kami, K, Tatsuno, T, Kobayashi, T, Shirai, Y, Lennartz, MR, Takeya, R, Sumimoto, H, Saito, N	J. Immunol.	2005