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MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm]
Stable Identifier
R-HSA-9005990
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by MECP2 (Homo sapiens)
MECP2 regulates neuronal receptors and channels (Homo sapiens)
GRIA2 gene expression is inhibited by MECP2:SIN3A complex (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2:GRIA2 gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A complex binds GRIA2 gene promoter (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2:GRIA2 gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A complex binds OPRM1 gene promoter (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC1:OPRM1 gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
OPRM1 gene expression is repressed by MECP2 (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC1:OPRM1 gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2 regulates transcription of neuronal ligands (Homo sapiens)
BDNF gene transcription (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
Regulation of MECP2 expression and activity (Homo sapiens)
MECP2 binds the SIN3A co-repressor complex (Homo sapiens)
MECP2:SIN3A:HDAC1,HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
9620804
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
Ng, HH
,
Nan, X
,
Bird, A
,
Turner, BM
,
Eisenman, RN
,
Laherty, CD
,
Johnson, CA
Nature
1998
Participants
components
MECP2 [nucleoplasm]
(Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Homo sapiens)
Participates
as a member of
MECP2:SIN3A:HDAC1,HDAC2 [nucleoplasm] (Homo sapiens)
as an input of
MECP2:SIN3A complex binds OPRM1 gene promoter (Homo sapiens)
MECP2:SIN3A complex binds GRIA2 gene promoter (Homo sapiens)
as a component of
MECP2:SIN3A:HDAC1:HDAC2:GRIA2 gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC1:OPRM1 gene [nucleoplasm] (Homo sapiens)
Inferred To
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Bos taurus)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Canis familiaris)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Mus musculus)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Rattus norvegicus)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Sus scrofa)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Xenopus tropicalis)
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