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RUNX2:RB1:BGLAP gene [nucleoplasm]
Stable Identifier
R-HSA-8985483
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX2 (Homo sapiens)
RUNX2 regulates bone development (Homo sapiens)
RUNX2 regulates osteoblast differentiation (Homo sapiens)
BGLAP gene expression is stimulated by RUNX2, WWTR1 and RB1 and inhibited by AR, YAP1 and ZNF521 (Homo sapiens)
RUNX2:RB1:BGLAP gene [nucleoplasm] (Homo sapiens)
RUNX2 and RB1 bind the BGLAP gene promoter (Homo sapiens)
RUNX2:RB1:BGLAP gene [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
11545733
The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation
Thomas, DM
,
Wang, WF
,
Carty, SA
,
Forrester, WC
,
Lee, JS
,
Hinds, PW
,
Piscopo, DM
Mol. Cell
2001
Participants
components
BGLAP gene [nucleoplasm]
(Homo sapiens)
RUNX2:RB1 [nucleoplasm]
(Homo sapiens)
Participates
as an output of
RUNX2 and RB1 bind the BGLAP gene promoter (Homo sapiens)
This entity regulates
Positively
BGLAP gene expression is stimulated by RUNX2, WWTR1 and RB1 and inhibited by AR, YAP1 and ZNF521
(Homo sapiens)
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