Reactome | p-MFGE8 [endoplasmic reticulum lumen]

p-MFGE8 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8957017

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

MFGE8, Lactadherin, MFGM_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q08431 MFGE8

Gene Names

MFGE8

Chain

signal peptide:1-23, chain:24-387, chain:202-387, chain:268-317

Reference Genes

BioGPS Gene:4240 MFGE8

COSMIC (genes):MFGE8 MFGE8

CTD Gene:4240 MFGE8

dbSNP Gene:4240 MFGE8

ENSEMBL:ENSG00000140545.16 MFGE8

HGNC:7036 MFGE8

KEGG Gene (Homo sapiens):4240 MFGE8

Monarch:4240 MFGE8

NCBI Gene:4240 MFGE8

OMIM:602281 MFGE8

UCSC:Q08431 MFGE8

Reference Transcript

Other Identifiers

11715508_x_at

11748084_a_at

11755066_x_at

16813038

210605_PM_s_at

210605_s_at

34403_at

3638205

3638206

3638207

3638208

3638209

3638210

3638211

3638213

3638214

3638221

3638222

3638223

3638224

3638225

3638226

3638232

3638233

4240

7991234

A_23_P48951

A_24_P133584

GE79849

GO:0001525

GO:0001786

GO:0002080

GO:0005178

GO:0005198

GO:0005201

GO:0005576

GO:0005615

GO:0005783

GO:0005788

GO:0005886

GO:0007155

GO:0007338

GO:0008289

GO:0009897

GO:0016020

GO:0016192

GO:0022414

GO:0030312

GO:0031012

GO:0031410

GO:0043226

GO:0043277

GO:0048856

GO:0062023

GO:0070062

GO:1903561

HMNXSV003023230

HMNXSV003031949

PH_hs_0000427

S56151_s_at

TC15001825.hg

U58516_at

g13177647_3p_x_at

Participates

as a member of

FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

MFGE8(268-317) [extracellular region]

MFGE8 [endoplasmic reticulum lumen]

Inferred To

phospho-mfge8l [endoplasmic reticulum lumen] (Danio rerio)

phospho-Mfge8 [endoplasmic reticulum lumen] (Mus musculus)

phospho-Mfge8 [endoplasmic reticulum lumen] (Rattus norvegicus)

phospho-MFGE8 [endoplasmic reticulum lumen] (Bos taurus)

phospho-MFGE8 [endoplasmic reticulum lumen] (Gallus gallus)

phospho-MFGE8 [endoplasmic reticulum lumen] (Sus scrofa)

phospho-mfge8 [endoplasmic reticulum lumen] (Xenopus tropicalis)

phospho-p-MFGE8 [endoplasmic reticulum lumen] (Canis familiaris)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_005919.2, NP_001108086.1, NP_001297249.1, NP_001297248.1, NP_001297250.1

OpenTargets

ENSG00000140545

GeneCards

Q08431

HPA

ENSG00000140545-MFGE8

Ensembl

ENSP00000456281, ENSG00000140545, ENSP00000444332, ENST00000268151, ENST00000566497, ENST00000268150, ENST00000542878, ENSP00000268150, ENSP00000268151

PRO

Q08431

Pharos - Targets

Q08431

HMDB Protein

HMDBP11590

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.527	2