p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor

Stable Identifier
R-HSA-8950441
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Signal transducer and activator of transcription 1-alpha/beta (STAT1) and Signal transducer and activator of transcription 3 (STAT3) dissociate from the receptor complex after activation.
This is a BlackBox event since the exact mechanism of this dissociation is unknown.

Literature References
PubMed ID Title Journal Year
18389480 IL-12, IL-23, and IL-27 enhance human beta-defensin-2 production in human keratinocytes

Kanda, N, Watanabe, S

Eur. J. Immunol. 2008
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created