RUNX2:CBFB binds the ITGA5 gene promoter

Stable Identifier
R-HSA-8939670
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RUNX2:CBFB binds the ITGA5 gene promoter
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RUNX2, presumably associated with CBFB, binds to OSE2 (osteoblast-specific cis-acting element 2) sites in the promoter of the ITGA5 gene, encoding Integrin alpha-5 (Li et al. 2016).

Literature References
PubMed ID Title Journal Year
27317874 RUNX2 promotes breast cancer bone metastasis by increasing integrin α5-mediated colonization

Lu, JT, Li, XQ, Feng, YM, Tan, CC, Wang, QS

Cancer Lett. 2016
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Authored
Orlic-Milacic, M  (2016-09-20)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2016-09-20)
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