RUNX1 binds PAX5 (BSAP)

Stable Identifier
R-HSA-8938951
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RUNX1 binds PAX5 (BSAP)
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The RUNX1:CBFB complex binds to PAX5, also known as BSAP (B-cell specific activating protein). The interaction involves the runt domain of RUNX1 and the paired DNA-binding domain of PAX5 (Libermann et al. 1999).

Literature References
PubMed ID Title Journal Year
10455134 AML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter

Pan, Z, Yergeau, DA, Hetherington, CJ, Akbarali, Y, Libermann, TA, Zhang, DE, Boltax, J

J. Biol. Chem. 1999
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Orthologous Events
RUNX1 binds PAX5 (BSAP) (Bos taurus)
RUNX1 binds PAX5 (BSAP) (Caenorhabditis elegans)
RUNX1 binds PAX5 (BSAP) (Danio rerio)
RUNX1 binds PAX5 (BSAP) (Drosophila melanogaster)
RUNX1 binds PAX5 (BSAP) (Gallus gallus)
RUNX1 binds PAX5 (BSAP) (Mus musculus)
RUNX1 binds PAX5 (BSAP) (Rattus norvegicus)
RUNX1 binds PAX5 (BSAP) (Sus scrofa)
Authored
Orlic-Milacic, M  (2016-09-14)
Reviewed
Chuang, LS  (2016-12-20)
Ito, Y  (2016-12-20)
Created
Orlic-Milacic, M  (2016-09-14)
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