RUNX1:CBFB:CREBBP binds the CSF2 (GM-CSF) gene promoter

Stable Identifier
R-HSA-8938228
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The complex of the RUNX1:CBFB heterodimer and histone acetyltransferase CREBBP (CBP) binds the promoter of the CSF2 (GM-CSF) gene, encoding Granulocyte-macrophage colony-stimulating factor (Oakford et al. 2010). RUNX1 can also recruit the SWI/SNF complex to the CSF2 gene promoter (Bakshi et al. 2010).

Literature References
PubMed ID Title Journal Year
20439113 Transcriptional and epigenetic regulation of the GM-CSF promoter by RUNX1

Oakford, PC, James, SR, Qadi, A, West, AC, Ray, SN, Bert, AG, Cockerill, PN, Holloway, AF

Leuk. Res. 2010
Participants
Participant Of
Authored
Reviewed
Created