RUNX1 binds FOXP3

Stable Identifier
R-HSA-8877192
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
RUNX1 binds FOXP3
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

RUNX1 forms a complex with FOXP3. This interaction involves the C-terminus of RUNX1 and the FOXP3 region between the forkhead domain and the leucine zipper motif (Ono et al. 2007).

Literature References
PubMed ID Title Journal Year
17377532 Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

Nagamura, Y, Ono, M, Kitabayashi, I, Tsukada, T, Ohkura, N, Sakaguchi, S, Nomura, T, Yaguchi, H, Miyachi, Y

Nature 2007
Participants
Input
Output
Participates
as an event of
Orthologous Events
RUNX1 binds FOXP3 (Bos taurus)
RUNX1 binds FOXP3 (Caenorhabditis elegans)
RUNX1 binds FOXP3 (Danio rerio)
RUNX1 binds FOXP3 (Drosophila melanogaster)
RUNX1 binds FOXP3 (Mus musculus)
RUNX1 binds FOXP3 (Rattus norvegicus)
RUNX1 binds FOXP3 (Sus scrofa)
Authored
Orlic-Milacic, M  (2016-09-14)
Reviewed
Chuang, LS  (2016-12-20)
Ito, Y  (2016-12-20)
Created
Orlic-Milacic, M  (2016-06-21)
Cite Us!