USP8 deubiquitinates LRIG1

Stable Identifier
R-HSA-8875443
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The ubiquitin hydrolase USP8 can deubiquitinate LRIG1, thus interfering with LRIG1-mediated MET downregulation (Oh et al. 2014).

Literature References
PubMed ID Title Journal Year
24828152 USP8 modulates ubiquitination of LRIG1 for Met degradation

Oh, YM, Lee, SB, Choi, J, Suh, HY, Shim, S, Song, YJ, Kim, B, Lee, JM, Oh, SJ, Jeong, Y, Cheong, KH, Song, PH, Kim, KA

Sci Rep 2014
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
thiol-dependent ubiquitin-specific protease activity of USP8 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created