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GGC-RAB35 [cytosol]
Stable Identifier
R-HSA-8873770
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ras-related protein Rab-35, RAB35_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
RAB geranylgeranylation (Homo sapiens)
RGGT geranylgeranylates RAB proteins (Homo sapiens)
CHMs:GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs [cytosol] (Homo sapiens)
GGC-RAB35 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
DENND1s exchange GTP for GDP on RAB35 (Homo sapiens)
GGC-RAB35:GDP:GDIs,CHMs [cytosol] (Homo sapiens)
GGC-RAB35:GDP [cytosol] (Homo sapiens)
GGC-RAB35 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15286 RAB35
Gene Names
RAB35, RAB1C, RAY
Chain
chain:1-201
Reference Genes
BioGPS Gene:11021 RAB35
COSMIC (genes):RAB35 RAB35
CTD Gene:11021 RAB35
dbSNP Gene:11021 RAB35
ENSEMBL:ENSG00000111737 RAB35
ENSEMBL_homo_sapiens_GENE:ENSG00000111737.12 RAB35
HGNC:9774 RAB35
KEGG Gene (Homo sapiens):11021 RAB35
Monarch:11021 RAB35
NCBI Gene:11021 RAB35
OMIM:604199 RAB35
UCSC:Q15286 RAB35
Reference Transcript
RefSeq:NM_006861.6 RAB35
RefSeq:NM_001167606.1 RAB35
Other Identifiers
11021
11722805_at
11722806_at
11746338_a_at
11753402_a_at
11753403_x_at
16771132
205461_PM_at
205461_at
221819_PM_at
221819_at
225620_PM_at
225620_at
3474229
3474230
3474231
3474232
3474233
3474234
3474235
3474238
3474240
3474248
3474249
3474250
35508_at
47561_at
47922_at
7966929
81598_at
A_23_P204482
A_23_P204484
GE55747
GE60055
GO:0000166
GO:0000278
GO:0000281
GO:0000910
GO:0002376
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005546
GO:0005576
GO:0005615
GO:0005768
GO:0005829
GO:0005886
GO:0005905
GO:0008104
GO:0008289
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0016197
GO:0016787
GO:0019003
GO:0019882
GO:0023052
GO:0030136
GO:0030154
GO:0030669
GO:0031175
GO:0031253
GO:0031410
GO:0032456
GO:0032482
GO:0036010
GO:0042470
GO:0043226
GO:0045171
GO:0045334
GO:0048227
GO:0048856
GO:0055038
GO:0070062
GO:1990090
HMNXSV003039533
Hs.94308.0.S1_3p_at
Hs.94308.0.S2_3p_at
ILMN_1812571
PH_hs_0029044
TC12002033.hg
TC12003119.hg
X79781_at
g5803134_3p_at
Participates
as a component of
GGC-RAB35:GDP [cytosol] (Homo sapiens)
as a candidate of
GGC-RABs [cytosol] (Homo sapiens)
Other forms of this molecule
RAB35 [clathrin-coated endocytic vesicle membrane]
GGC-RAB35 [recycling endosome membrane]
RAB35 [cytosol]
Inferred To
Homologues of GGC-RAB35 [cytosol]
(Dictyostelium discoideum)
rab-35 [cytosol]
(Caenorhabditis elegans)
RAB35 [cytosol]
(Bos taurus)
RAB35 [cytosol]
(Canis familiaris)
RAB35 [cytosol]
(Sus scrofa)
GGC-RAB35 [cytosol]
(Dictyostelium discoideum)
GGC-RAB35 [cytosol]
(Gallus gallus)
GGC-RAB35 [cytosol]
(Mus musculus)
GGC-RAB35 [cytosol]
(Rattus norvegicus)
Rab35 [cytosol]
(Drosophila melanogaster)
rab35 [cytosol]
(Xenopus tropicalis)
rab35b [cytosol]
(Danio rerio)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 200
Coordinate
200
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 201
Coordinate
201
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
RefSeq
NP_006852.1
,
NP_001161078.1
OpenTargets
ENSG00000111737
HPA
ENSG00000111737-RAB35
GeneCards
Q15286
Ensembl
ENST00000229340
,
ENST00000534951
,
ENSG00000111737
,
ENSP00000441883
,
ENSP00000229340
PRO
Q15286
Pharos - Targets
Q15286
PDB
6IF2
,
6IF3
,
6EKK
,
3TW8
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
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