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L-isoglutamyl polyglycyl-TUBA8 [cytosol]
Stable Identifier
R-HSA-8867462
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
TUBA8, Tubulin alpha-8 chain, TBA8_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Carboxyterminal post-translational modifications of tubulin (Homo sapiens)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Homo sapiens)
Polyglycylated microtubule [cytosol] (Homo sapiens)
Polyglycylated microtubule protofilament [cytosol] (Homo sapiens)
Polyglycyl alpha-beta tubulin dimer [cytosol] (Homo sapiens)
Polyglycyl alpha tubulin:GTP [cytosol] (Homo sapiens)
Polyglycyl alpha tubulin [cytosol] (Homo sapiens)
L-isoglutamyl polyglycyl-TUBA8 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NY65 TUBA8
Gene Names
TUBA8, TUBAL2
Chain
chain:1-449, chain:1-448
Reference Genes
BioGPS Gene:51807 TUBA8
COSMIC (genes):TUBA8 TUBA8
CTD Gene:51807 TUBA8
dbSNP Gene:51807 TUBA8
ENSEMBL:ENSG00000183785 TUBA8
ENSEMBL:ENSG00000183785.16 TUBA8
HGNC:12410 TUBA8
KEGG Gene (Homo sapiens):51807 TUBA8
Monarch:51807 TUBA8
NCBI Gene:51807 TUBA8
OMIM:605742 TUBA8
UCSC:Q9NY65 TUBA8
Reference Transcript
RefSeq:NM_001193414.1 TUBA8
RefSeq:NM_018943.2 TUBA8
Other Identifiers
11755698_a_at
16926932
220069_PM_at
220069_at
3936516
3936517
3936518
3936519
3936521
3936523
3936525
3936527
3936528
3936529
3936534
51807
61935_at
8071147
A_24_P160104
GE55290
GO:0000166
GO:0000226
GO:0000278
GO:0001669
GO:0003824
GO:0005198
GO:0005200
GO:0005515
GO:0005525
GO:0005737
GO:0005856
GO:0005874
GO:0007010
GO:0007017
GO:0007283
GO:0007286
GO:0015630
GO:0016787
GO:0022414
GO:0030154
GO:0031410
GO:0043226
GO:0046872
GO:0048856
HMNXSV003032933
ILMN_1793659
PH_hs_0008290
TC22001452.hg
g9507214_3p_at
Participates
as a candidate of
Polyglycyl alpha tubulin [cytosol] (Homo sapiens)
Other forms of this molecule
AcK-TUBA8 [cytosol]
TUBA8 folding intermediate [cytosol]
TUBA8 unfolded [cytosol]
Polyglutamyl-TUBA8 [cytosol]
TUBA8 [cytosol]
Inferred To
Homologues of L-isoglutamyl polyglycyl-TUBA1C [cytosol]
(Dictyostelium discoideum)
Homologues of L-isoglutamyl polyglycyl-TUBA1C [cytosol]
(Plasmodium falciparum)
L-isoglutamyl polyglycyl-TUBA8 [cytosol]
(Bos taurus)
L-isoglutamyl polyglycyl-TUBA8 [cytosol]
(Gallus gallus)
L-isoglutamyl polyglycyl-TUBA8 [cytosol]
(Mus musculus)
L-isoglutamyl polyglycyl-TUBA8 [cytosol]
(Rattus norvegicus)
L-isoglutamyl polyglycyl-TUBA1C [cytosol]
(Dictyostelium discoideum)
L-isoglutamyl polyglycyl-TUBA1C [cytosol]
(Plasmodium falciparum)
TUBA8 [cytosol]
(Sus scrofa)
Modified Residues
Name
L-isoglutamyl-polyglycine at unknown position
PsiMod Name
L-isoglutamyl-polyglycine
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-isoglutamyl-polyglycine.
Cross References
RefSeq
NP_001180343.1
,
NP_061816.1
OpenTargets
ENSG00000183785
GeneCards
Q9NY65
HPA
ENSG00000183785-TUBA8
Ensembl
ENST00000416740
,
ENSG00000183785
,
ENSP00000318575
,
ENSP00000333326
,
ENST00000316027
,
ENST00000330423
,
ENSP00000412646
PRO
Q9NY65
Pharos - Targets
Q9NY65
Orphanet
19847
HMDB Protein
HMDBP08599
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
3
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