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ALKBH5 [nucleoplasm]
Stable Identifier
R-HSA-8857700
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
fullName evidence="20"RNA demethylase ALKBH5 ecNumber1.14.11.-/ecNumber, ALKB5_HUMAN
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Damage Reversal (Homo sapiens)
Reversal of alkylation damage by DNA dioxygenases (Homo sapiens)
RNA demethylases demethylate N6-methyladenosine RNA (Homo sapiens)
RNA demethylases [nucleoplasm] (Homo sapiens)
ALKBH5:Fe2+ [nucleoplasm] (Homo sapiens)
ALKBH5 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6P6C2 ALKBH5
Gene Names
ALKBH5, ABH5, OFOXD1
Chain
initiator methionine:, chain:2-394
Reference Genes
BioGPS Gene:54890 ALKBH5
COSMIC (genes):ALKBH5 ALKBH5
CTD Gene:54890 ALKBH5
dbSNP Gene:54890 ALKBH5
ENSEMBL:ENSG00000091542 ALKBH5
HGNC:25996 ALKBH5
KEGG:hsa:54890 ALKBH5
Monarch:54890 ALKBH5
NCBI Gene:54890 ALKBH5
OMIM:613303 ALKBH5
UCSC:Q6P6C2 ALKBH5
Reference Transcript
RefSeq:NM_017758.3 ALKBH5
Other Identifiers
11719043_x_at
11719044_s_at
11751450_a_at
1553101_PM_a_at
1553101_a_at
16831789
228034_PM_x_at
228034_x_at
234302_PM_s_at
234302_s_at
3713094
3713095
3713096
3713097
3713098
3713099
3713100
3713101
3713111
3713117
3713118
3713119
3713120
3713121
3713122
3713123
3713124
54890
56414_at
8005399
A_23_P153050
A_23_P416169
A_33_P3239854
GE55440
GO:0001666
GO:0002376
GO:0003723
GO:0003824
GO:0005634
GO:0005654
GO:0005794
GO:0005829
GO:0006397
GO:0006406
GO:0006417
GO:0006913
GO:0007283
GO:0010793
GO:0016071
GO:0016491
GO:0016607
GO:0016706
GO:0022414
GO:0030154
GO:0035515
GO:0042382
GO:0043226
GO:0043488
GO:0046630
GO:0046872
GO:0050684
GO:0051213
GO:0060090
GO:0061157
GO:0140098
GO:0140693
GO:0140694
GO:1990931
HMNXSV003020751
Hs.130740.2.S1_3p_s_at
Hs.169476.2.A1_3p_at
Hs2.130740.1.S1_3p_s_at
ILMN_1657283
PH_hs_0024005
TC17000207.hg
Participates
as a component of
ALKBH5:Fe2+ [nucleoplasm] (Homo sapiens)
Inferred To
ALKBH5 [nucleoplasm]
(Bos taurus)
ALKBH5 [nucleoplasm]
(Canis familiaris)
ALKBH5 [nucleoplasm]
(Danio rerio)
ALKBH5 [nucleoplasm]
(Gallus gallus)
ALKBH5 [nucleoplasm]
(Mus musculus)
ALKBH5 [nucleoplasm]
(Rattus norvegicus)
ALKBH5 [nucleoplasm]
(Sus scrofa)
ALKBH5 [nucleoplasm]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000382091
,
ENSG00000091542
,
ENST00000399138
OpenTargets
ENSG00000091542
GeneCards
ALKBH5
HPA
ENSG00000091542-ALKBH5
PRO
Q6P6C2
Pharos - Targets
Q6P6C2
PDB
4NRP
,
7WKV
,
7WL0
,
4NRO
,
4OCT
,
4O7X
,
4O61
,
7V4G
,
4NRM
,
4NRQ
,
4NJ4
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P52294 KPNA1
2
KPNA1 [cytosol]
(R-HSA-180612)
KPNA1 [nucleoplasm]
(R-HSA-188865)
0.527
2
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