Reactome | PALM-C36-ASGR1 [plasma membrane]

PALM-C36-ASGR1 [plasma membrane]

Stable Identifier

R-HSA-8855714

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Asialoglycoprotein receptor 1, ASGR1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P07306 ASGR1

Gene Names

ASGR1, CLEC4H1

Chain

chain:1-291

Reference Genes

BioGPS Gene:432 ASGR1

COSMIC (genes):ASGR1 ASGR1

CTD Gene:432 ASGR1

dbSNP Gene:432 ASGR1

ENSEMBL:ENSG00000141505 ASGR1

ENSEMBL:ENSG00000141505.12 ASGR1

HGNC:742 ASGR1

KEGG Gene (Homo sapiens):432 ASGR1

Monarch:432 ASGR1

NCBI Gene:432 ASGR1

OMIM:108360 ASGR1

UCSC:P07306 ASGR1

Reference Transcript

Other Identifiers

11728559_a_at

11745554_a_at

16840502

206743_PM_s_at

206743_s_at

3743372

3743373

3743374

3743376

3743378

3743380

3743383

3743384

3743386

3743389

3743390

3743391

3743392

37519_at

432

8012043

A_23_P118722

GE62069

GO:0004873

GO:0005515

GO:0005537

GO:0005576

GO:0005886

GO:0006897

GO:0006898

GO:0009897

GO:0016020

GO:0016192

GO:0030246

GO:0031668

GO:0038024

GO:0042802

GO:0042806

GO:0046872

HMNXSV003058203

ILMN_1769013

M10058_at

PH_hs_0001130

PH_hs_0035347

TC17001076.hg

g4502250_3p_a_at

Participates

as a component of

PALM-C36-ASGR1:PALM-C54,58-ASGR2 [plasma membrane] (Homo sapiens)

Inferred To

Homologues of PALM-C36-ASGR1 [plasma membrane] (Danio rerio)

BEST:GH10831 [plasma membrane] (Drosophila melanogaster)

ASGR1 [plasma membrane] (Bos taurus)

ASGR1 [plasma membrane] (Sus scrofa)

PALM-C36-ASGR1 [plasma membrane] (Canis familiaris)

PALM-C36-ASGR1 [plasma membrane] (Danio rerio)

PALM-C36-ASGR1 [plasma membrane] (Mus musculus)

PALM-C36-ASGR1 [plasma membrane] (Rattus norvegicus)

clec-1 [plasma membrane] (Caenorhabditis elegans)

LOC101732610 [plasma membrane] (Xenopus tropicalis)

Modified Residues

Name

N-palmitoyl-L-cysteine at 36

Coordinate

PsiMod Name

N-palmitoyl-L-cysteine [MOD:00069]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-L-cysteine.

Cross References

RefSeq

NP_001662.1, XP_011522163.1, NP_001184145.1

OpenTargets

ENSG00000141505

GeneCards

P07306

HPA

ENSG00000141505-ASGR1

Ensembl

ENSP00000459169, ENST00000269299, ENST00000619926, ENSG00000141505, ENSP00000481182, ENSP00000269299, ENST00000574388

PRO

P07306

Pharos - Targets

P07306

PDB

6YAU, 1DV8, 5JQ1, 5JPV

HMDB Protein

HMDBP07462

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P24593 IGFBP5	5	IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956738) p-IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956988) IGFBP5 [extracellular region] (R-HSA-381414) IGFBP5(21-163) [extracellular region] (R-HSA-381415) IGFBP5(164-272) [extracellular region] (R-HSA-381478)	0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:A8MZ59 LEUTX	1	LEUTX [nucleoplasm] (R-HSA-9817277)	0.556	3
UniProt:Q14973 SLC10A1	1	SLC10A1 [plasma membrane] (R-HSA-194116)	0.556	3
UniProt:Q9UN42 ATP1B4	1	ATP1B4 [nuclear envelope] (R-HSA-939761)	0.556	3

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