Reactome | FLOT2 [plasma membrane]

FLOT2 [plasma membrane]

Stable Identifier

R-HSA-8849895

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Flotillin-2, FLOT2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14254 FLOT2

Gene Names

FLOT2, ESA1, M17S1

Chain

initiator methionine:, chain:2-428

Reference Genes

BioGPS Gene:2319 FLOT2

COSMIC (genes):FLOT2 FLOT2

CTD Gene:2319 FLOT2

dbSNP Gene:2319 FLOT2

ENSEMBL:ENSG00000132589 FLOT2

ENSEMBL_homo_sapiens_GENE:ENSG00000132589.16 FLOT2

HGNC:3758 FLOT2

KEGG Gene (Homo sapiens):2319 FLOT2

Monarch:2319 FLOT2

NCBI Gene:2319 FLOT2

OMIM:131560 FLOT2

UCSC:Q14254 FLOT2

Reference Transcript

Other Identifiers

11716295_at

11716296_at

16842834

201350_PM_at

201350_at

211299_PM_s_at

211299_s_at

2319

32181_at

3751124

3751125

3751126

3751127

3751128

3751129

3751130

3751131

3751132

3751133

3751134

3751136

3751137

3751138

3751139

3751141

3751142

3751144

3751150

3751155

3751156

3751157

52561_s_at

8013788

A_23_P55319

A_24_P253818

GE61554

GE87893

GO:0001931

GO:0002080

GO:0002376

GO:0005515

GO:0005576

GO:0005615

GO:0005768

GO:0005856

GO:0005886

GO:0005901

GO:0005912

GO:0005925

GO:0007018

GO:0007155

GO:0007163

GO:0008544

GO:0010629

GO:0016020

GO:0016323

GO:0016600

GO:0023052

GO:0030027

GO:0030139

GO:0030154

GO:0030864

GO:0031410

GO:0031982

GO:0032839

GO:0043123

GO:0043226

GO:0043231

GO:0044291

GO:0044860

GO:0045121

GO:0045661

GO:0048471

GO:0048856

GO:0050821

GO:0070062

GO:0072659

GO:0098937

GO:0098978

GO:0099072

GO:1902992

GO:1903905

HMNXSV003044759

ILMN_1726222

ILMN_1790781

M60922_at

PH_hs_0022019

TC17001311.hg

g13277549_3p_a_at

g4758393_3p_at

Participates

as a candidate of

as a member of

FLOT1(FLOT2) [plasma membrane] (Homo sapiens)

as a component of

FLOT1:FLOT2 [plasma membrane] (Homo sapiens)

Inferred To

flot2a [plasma membrane] (Danio rerio)

flot2 [plasma membrane] (Xenopus tropicalis)

Flot2 [plasma membrane] (Mus musculus)

Flot2 [plasma membrane] (Rattus norvegicus)

FLOT2 [plasma membrane] (Bos taurus)

FLOT2 [plasma membrane] (Canis familiaris)

FLOT2 [plasma membrane] (Gallus gallus)

FLOT2 [plasma membrane] (Sus scrofa)

Flo2 [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

XP_016879883.1, XP_016879884.1, NP_004466.2

OpenTargets

ENSG00000132589

GeneCards

Q14254

HPA

ENSG00000132589-FLOT2

Ensembl

ENSG00000132589, ENST00000394908, ENSP00000378368

PRO

Q14254

Pharos - Targets

Q14254

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	12

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