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AIM2 oligomerizes
Stable Identifier
R-HSA-874079
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Homo sapiens)
Inflammasomes (Homo sapiens)
The AIM2 inflammasome (Homo sapiens)
AIM2 oligomerizes (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
AIM2 oligomerizes, forming AIM2 clusters that are able to interact with ASC (Fernandes-Alnemri et al. 2009, Hornung et al. 2009). The extent of oligomerization required is unknown.
Participants
Input
dsDNA:AIM2 [cytosol]
(Homo sapiens)
Output
dsDNA:AIM2 oligomer [cytosol]
(Homo sapiens)
Participates
as an event of
The AIM2 inflammasome (Homo sapiens)
Inferred From
Aim2 oligomerizes (Mus musculus)
Authored
Jupe, S (2010-04-22)
Reviewed
Kufer, TA (2011-04-28)
Rittinger, K (2011-06-06)
Wong, E (2011-06-06)
Created
Jupe, S (2010-06-10)
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